Researchers from Yale Cancer Center (New Haven, CT, USA) have investigated the clinical benefits of chemotherapy treatment for adult medulloblastoma patients, with results suggesting that it may improve survival rates.
In a proof-of-concept study, researchers have demonstrated that an experimental PET tracer could be used to effectively diagnose concussion-related CTE in living patients.
Researchers from the Developmental Biology Institute of Marseille (France) and Manchester University (UK) have identified a gene termed ‘Teashirt’ as a potential link between kidney deficits and autism spectrum disorder in children, which could influence how clinicians treat patients.
This study aimed to replicate prior findings, hypothesizing that CYP2D6 UM status would be associated with previous suicide attempt in a sample of more than 4200 inpatients recruited from three state psychiatric hospitals in the USA.
This study utilized SILAC proteomic analysis of human ALS patient and population control fibroblasts to discover proteins that are differentially regulated in ALS and may serve as useful biomarkers.
In this review, the authors highlight the recent progress in TD genetic research with a particular focus since 2011. They review genes involved in antipsychotic drug metabolism (pharmacokinetics) and those involved in drug targeting (pharmacodynamics), and provide a number of recommendations to move this area of research forward.