Original Publication Date: >10 September, 2015
Publication / Source: Future Science OA
Authors: Joana A Loureiro, Bárbara Gomes, Manuel AN Coelho, Maria do Carmo Pereira & Sandra Rocha
Aim: The present study was designed to test the cellular uptake of PEGylated liposomes targeted to transferrin receptor and to α-synuclein by a cell model of the blood–brain barrier (BBB). Materials & methods: PEGylated immunoliposomes were prepared with anti-transferrin receptor OX26 and anti-α-synuclein LB509 antibodies to overcome the BBB in Parkinson’s disease.