Neurology Central

Advancing cerebrospinal fluid biomarker discovery by mass spectrometry

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Cerebrospinal fluid (CSF) is an important source of biomarkers of neurodegenerative diseases [1]. Reflecting biochemical processes in the brain, proteins in the CSF may reveal clues to disease mechanisms. As new disease-modifying therapies are being developed, there is an increased need for markers that enable earlier, more accurate diagnosis and provide means to monitor disease progression and response to treatment.

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