Neurology Central

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoancepahlopathy presenting with postpartum psychosis and late-onset stroke

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Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoancepahlopathy (CADASIL) due to ∼200 identified mutations in NOTCH 3 gene (chromosome 19) is the most common cause of inherited cerebral small vessel disease, inherited stroke and inherited vascular cognitive decline [1]. Typically, symptom onset is with migraine with aura at about the age of 30 years or early stroke at 41–50 years.
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