Researchers use epigenome-editing technology to repress cytokine cell receptors, preventing tissue degeneration and pain.
Dr Coffman is currently studying the mechanisms by which chronic early-life stress increases adult disease risk, using zebrafish as a model organism to ask how such stress affects immune system development and regulation.
Live event: Thursday 13th April 2017 at 07:00 [PDT] 10:00 [EDT] 15:00 [BST]
Epidemiological studies have shown that chronic stress experienced very early in life—even prenatally—increases the risk of developing inflammatory disease in adulthood, including mental health disorders such as anxiety and depression.
Study also reveals differences in the metabolism of macular telangiectasia sufferers that could lead to onset of the disease.
In this interview, Drs Silverman and Buscher discuss their work, and how these two rare diseases are shedding light not only on each other, but also a wealth of other neurological disorders.
A recent study has identified a cellular pathway that that may lead to the protein misfolding observed in those diagnosed with Huntington’s disease.
Researchers have uncovered a role for the gene FKBP5 in memory formation following traumatic events, and suggest that manipulation of the gene could help prevent PTSD.
Researchers report the restoration of higher levels of hearing – the equivalent of a whisper – in genetically deaf mice using a gene therapy vector.
Research identifies 30 genes that could one day be utilized as therapeutic targets for Rett syndrome.
Researchers have successfully reduced tau deposits and prevented neuronal death with novel drug in both mouse and primate models.