Karmakar & Reilly review what is known about the role of NF1 mutation in immune cell function & the role of immune cells in promoting tumorigenesis in NF1.
New research has elucidated a pathway in diffuse intrinsic pontine glioma with promise for therapeutic targeting.
Immunotherapy for glioblastoma has been an area of intense research in recent years – this review looks at the potential of HCMV in the initiation, promotion and progression of tumorigenesis.
For the first time, researchers describe the pathological features of a severe liver-injury associated with the administration of the anti–PD-1 agent nivolumab in a patient with glioblastoma.
Christian Naus discusses his work on 3D glioma models, which could facilitate personalized medicine approaches to one of the brain’s most significant threats.
Natsume et al. summarize approaches with adoptive immunotherapies using genetically modified T cells, which have been improved by enhancing their antitumor activity, and discuss strategies to further develop these therapies.
A group of researchers from the Dana-Farber Cancer Institute (MA, USA) has conducted the largest clinical study to date of genetic abnormalities in pediatric brain tumors.
This article reviews new vaccination protocols against glioblastoma, as well as new the prospect of novel combination therapies.
Lauren Pulling highlights some of the key trending topics in neurology and neuroscience from 2016, as well as the top read articles of the year – take a look and let us know your thoughts.
In this article, the authors report the case of a patient suffering from a melanoma with multiple brain metastasis, treated with BRAF and MEK double blockade, with impressive and rapid response.